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GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility.

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成果类型:
期刊论文
作者:
Wei, Wei;Pan, Shuang;Ma, Yuemin;Xiao, Yutao;Yang, Yongbo;...
通讯作者:
Liu, Kaiyu;Soberon, Mario
作者机构:
[Liu, Kaiyu; Wei, Wei; Yang, Yongbo; Pan, Shuang; He, Sijia; Ma, Yuemin] Cent China Normal Univ, Sch Life Sci, Wuhan 430070, Peoples R China.
[Xiao, Yutao] Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen 518120, Peoples R China.
[Soberon, Mario; Bravo, Alejandra] Univ Nacl Autonoma Mexico, Inst Biotecnol, Apdo Postal 510-3, Cuernavaca 62250, Morelos, Mexico.
通讯机构:
[Liu, Kaiyu] C
[Soberon, Mario] U
Cent China Normal Univ, Sch Life Sci, Wuhan 430070, Peoples R China.
Univ Nacl Autonoma Mexico, Inst Biotecnol, Apdo Postal 510-3, Cuernavaca 62250, Morelos, Mexico.
语种:
英文
关键词:
Bacillus thuringiensis;Cry toxin;Cry toxin-receptor gene promoter;GATA transcription factor;Helicoverpa armigera;Insect cell line;Midgut tissue
期刊:
Insect Biochemistry and Molecular Biology
ISSN:
0965-1748
年:
2020
卷:
118
页码:
103306
基金类别:
This work was supported by the National Key R &D Program of China (grant number: 2017YFD0200400 ). Appendix A
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
The insecticidal Cry toxins produced by Bacillus thuringiensis (Bt) are powerful tools for insect control. Cry toxin receptors such as cadherin (CAD), ABCC2 transporter and alkaline phosphatase (ALP), located on insect midgut cells, are needed for Cry toxicity. Although insect cell lines are useful experimental models for elucidating toxin action mechanism, most of them show low expression of Cry-receptors genes. The GATA transcription factor family plays important roles in regulating development and differentiation of intestine stem cells. Her...

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