The work is partially supported by the National Key Research and Development Program of China (2017YFC0909502), the National Natural Science Foundation of China (61532008 and 61872157), the Wuhan Science and Technology Program (2019010701011392), the Key Research Program of Central China Normal University (CCNU18JCXK05), the Fundamental Research Funds for the Central Universities (CCNU19TD004), the Guangxi Key Laboratory of Trusted Software (No. kx201905), and the Research Fund of Guangxi Key Lab of Multi-source Information Mining & Security (MIMS19-02). The views presented in this paper are those of the authors and do not necessarily represent those of the US Food and Drug Administration.