期刊论文

The neuropsychological mechanism of therapy in depression and anxiety disorder: A meta-analysis of functional neuroimaging studies

中文

心理学报

0439-755X

2017

49

10

1302-1321

10.3724/SP.J.1041.2017.01302

国家社科基金项目(16CSH051)

本校为其他机构

抑郁障碍和焦虑障碍是两种最常见的精神障碍。使用激活似然估计(activation likelihood estimation, ALE)元分析对抑郁和焦虑障碍患者治疗后出现的一致脑区激活改变进行评估,并考察不同条件下这一改变的差异。研究共纳入25篇文献,结果发现:(1)抑郁和焦虑障碍接受治疗后,枕下回(inferior occipital gyrus, IOG)等脑区激活增加;豆状核(lentiform nucleus)等激活减少。(2) a.心理治疗产生的脑激活改变为豆状核活动的减少;药物治疗则在于扣带回(cingulate gyrus)等活动增加,而楔前叶(precuneus)等活动减少。b.任务下成像治疗后激活增加的脑区为扣带回等,减少的脑区为楔前叶等;静息下成像,治疗后枕下...

Some commonality is assumed between depression and anxiety disorder in terms of brain regions that are responsible for the disorder and treatment effect. However empirical evidence is lacking due to the fact that most studies investigating treatment effect on activating change in abnormal brain regions only focused on one of the two disorders. The current study, using meta-analysis, explored the types of neuropsychological commonality between depression and anxiety disorder. Additionally, discrepancies in brain activity change between depression and anxiety disorder due to treatment methods (p...