Numerous studies have revealed that an enriched environment can enhance the survival-related behaviors and brain functions of animals. However, the effects and specific roles of the enrichment characteristics on animals’ innovative capability, a cognitive ability crucial for survival in nature, are still not well known. In this study, we assigned mice to environment-manipulation groups (n = 15 each) to investigate the specific effects of environmental novelty (novel vs. familiar) and environmental complexity (complex vs. normal) on innovative ...