Aryldiazonium Salts Serve as a Dual Synthon: Construction of Fully Substituted Pyrazoles via Rongalite-Mediated Three-Component Radical Annulation Reaction
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21472056, 21602070, 21772051]; 111 ProjectMinistry of Education, China - 111 Project [B17019]
机构署名：
本校为通讯机构
院系归属：
化学学院
摘要：
A highly efficient rongalite-mediated three-component radical annulation reaction to furnish fully substituted pyrazoles from aryldiazonium salts and alpha,beta-unsaturated aldehydes or ketones under metal- and oxidant-free conditions at room temperature has been developed. In this transformation, aryldiazonium salts served as the precursor of both the aryl and aryl hydrazine units. Mechanistic investigations indicated that rongalite could act as a radical in...
