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Inferring microbial interaction networks based on consensus similarity network fusion

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成果类型:
期刊论文
作者:
Jiang XingPeng(蒋兴鹏);Hu XiaoHua*
通讯作者:
Hu XiaoHua
作者机构:
[Jiang XingPeng] Drexel Univ, Coll Comp & Informat, Philadelphia, PA 19104 USA.
[Jiang XingPeng; Hu XiaoHua] Cent China Normal Univ, Sch Comp, Wuhan 430079, Peoples R China.
通讯机构:
[Hu XiaoHua] C
Cent China Normal Univ, Sch Comp, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
species interaction;metagenome;diffusion process;biological network;modularity
关键词(中文):
微生物群落;网络融合;相互作用;相似性;数据集成;生物物种;模块化结构;宏基因组
期刊:
中国科学:生命科学(英文版)
ISSN:
1674-7305
年:
2014
卷:
57
期:
11
页码:
1115-1120
基金类别:
US National Science Foundation, Division of Industrial Innovation and PartnershipsNational Science Foundation (NSF) [1160960, 1332024]; Computing and Communication Foundations [0905291]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [90920005, 61170189]; Twelfth Five-year Plan of China [2012BAK24B01]; National Social Science Funds of China [122D223, 13ZD183]; Division of Computing and Communication FoundationsNational Science Foundation (NSF)NSF - Directorate for Computer & Information Science & Engineering (CISE) [0905291] Funding Source: National Science Foundation
机构署名:
本校为通讯机构
院系归属:
计算机学院
摘要:
With the rapid accumulation of high-throughput metagenomic sequencing data, it is possible to infer microbial species relations in a microbial community systematically. In recent years, some approaches have been proposed for identifying microbial interaction network. These methods often focus on one dataset without considering the advantage of data integration. In this study, we propose to use a similarity network fusion (SNF) method to infer microbial relations. The SNF efficiently integrates the similarities of species derived from different datasets by a cross-network diffusion process. We ...

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