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Dynamic steric confinement effect expands the frontier of Cu-catalyzed asymmetric propargylic aminations

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成果类型:
期刊论文
作者:
Peng Chen;Mao-Mao Zhang;Wen-Jing Xiao;Liang-Qiu Lu*
通讯作者:
Liang-Qiu Lu
作者机构:
[Peng Chen; Mao-Mao Zhang] Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China
Wuhan Institute of Photochemistry and Technology, Wuhan, China
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences, Lanzhou, China
School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, China
[Wen-Jing Xiao] Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China<&wdkj&>Wuhan Institute of Photochemistry and Technology, Wuhan, China
通讯机构:
[Liang-Qiu Lu] E
Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China<&wdkj&>Wuhan Institute of Photochemistry and Technology, Wuhan, China<&wdkj&>State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences, Lanzhou, China<&wdkj&>School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, China
语种:
中文
期刊:
中国科学:化学英文版
ISSN:
1674-7291
年:
2024
卷:
67
期:
10
页码:
3181-3183
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
Chiral α-tertiary amines and related azacycles are commonly found in many natural products, pharmaceuticals and agrochemicals [1]. Copper-catalyzed asymmetric propargylic amination(APA) reactions have been established as a reliable method to access enantio-enriched propargylic amines,largely due to the seminal contribution of Nishibayashi et al.[2] and...

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