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A Novel Sterol Regulatory Element-Binding Protein Gene (sreA) Identified in Penicillium digitatum Is Required for Prochloraz Resistance, Full Virulence and erg11 (cyp51) Regulation

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成果类型:
期刊论文
作者:
Liu, Jing;Yuan, Yongze(袁永泽);Wu, Zhi;Li, Na;Chen, Yuanlei;...
通讯作者:
Liu, Deli
作者机构:
[Yuan, Yongze; Xiong, Li; Liu, Jing; Liu, Deli; Chen, Yuanlei; Wu, Zhi; Li, Na; Geng, Hui; Qin, Tingting] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Liu, Deli] C
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Polymerase chain reaction;Transcription factors;Fungal genetics;Gene regulation;Gene expression;Fungi;Sterols;Fungicides
期刊:
PLOS ONE
ISSN:
1932-6203
年:
2015
卷:
10
期:
2
页码:
e0117115
基金类别:
National Natural Science Foundations of ChinaNational Natural Science Foundation of China (NSFC) [31371893, 31071653, 31101595]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Penicillium digitatum is the most destructive postharvest pathogen of citrus fruits, causing fruit decay and economic loss. Additionally, control of the disease is further complicated by the emergence of drug-resistant strains due to the extensive use of triazole antifungal drugs. In this work, an orthologus gene encoding a putative sterol regulatory element-binding protein (SREBP) was identified in the genome of P. digitatum and named sreA. The putative SreA protein contains a conserved domain of unknown function (DUF2014) at its carboxyl terminus and a helix-loop-helix (HLH) leucine zipper D...

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