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Vitamin E reduces the extent of mouse brain damage induced by combined exposure to formaldehyde and PM2.5.

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成果类型:
期刊论文
作者:
Liu, Xudong;Zhang, Yuchao;Yang, Xu*
通讯作者:
Yang, Xu
作者机构:
[Yang, Xu; Zhang, Yuchao; Liu, Xudong] Moutai Inst, Dept Food Sci & Engn, Renhuai 564507, Peoples R China.
[Yang, Xu] Cent China Normal Univ, Coll Life Sci, Lab Environm Biomed, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Yang, Xu] M
Moutai Inst, Dept Food Sci & Engn, Renhuai 564507, Peoples R China.
语种:
英文
关键词:
Brain damage;Co-exposure;Protective effects;Vitamin E
期刊:
Ecotoxicology and Environmental Safety
ISSN:
0147-6513
年:
2019
卷:
172
页码:
33-39
基金类别:
This work was supported by the Regular Undergraduate Institutions Nature Science Research Project of Guizhou Education Department (Technology top-notch talent support project QianjiaoheKYzi[2018]083 ).
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Exposure to specific air pollutants has been demonstrated to induce damage in the brain. However, these studies ignore the effects of a combination of contaminants, and there is a high likelihood that people will be exposed to a mixture of contaminants in daily life. Our previous study showed that co-exposure to formaldehyde (FA) and PM2.5 induced damage in the mouse brain at the safe exposure level for FA or PM2.5 exposure alone, and that oxidative stress and inflammation may be involved in the toxicity mechanisms. A universal strategy to prot...

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