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GNPI: Graph normalization to integrate phylogenetic information for metagenomic host phenotype prediction

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成果类型:
期刊论文
作者:
Li, Bojing;Zhong, Duo;Qiao, Jimei;Jiang, Xingpeng
通讯作者:
Xingpeng Jiang
作者机构:
[Zhong, Duo; Jiang, Xingpeng; Li, Bojing] Cent China Normal Univ, Hubei Key Lab Artificial Intelligence & Smart Lear, Wuhan, Peoples R China.
[Zhong, Duo; Jiang, Xingpeng; Li, Bojing] Cent China Normal Univ, Sch Comp, Wuhan, Peoples R China.
[Qiao, Jimei] Shanghai Normal Univ, Math & Sci Coll, Shanghai, Peoples R China.
[Jiang, Xingpeng] Cent China Normal Univ, Natl Language Resources Monitoring & Res Ctr Netwo, Wuhan, Peoples R China.
通讯机构:
[Xingpeng Jiang] H
Hubei Key Laboratory of Artificial Intelligence and Smart Learning, Central China Normal University, Wuhan, China<&wdkj&>School of Computer, Central China Normal University, Wuhan, China<&wdkj&>National Language Resources Monitoring & Research Center for Network Media, Central China Normal University, Wuhan, China
语种:
英文
关键词:
Graph neural networks;Graph normalization;Host phenotype prediction;Metagenomics
期刊:
Methods
ISSN:
1046-2023
年:
2022
卷:
205
页码:
11-17
基金类别:
National Natural Science Foun-dation of China [61872157, 61932008]; Key Research and Development Program of Hubei Province [2020BAB017]
机构署名:
本校为第一机构
院系归属:
计算机学院
摘要:
Microorganisms play important roles in our lives especially on metabolism and diseases. Determining the probability of human suffering from specific diseases and the severity of the disease based on microbial genes is the crucial research for understanding the relationship between microbes and diseases. Previous could extract the topological information of phylogenetic trees and integrate them to metagenomic datasets, thus enable classifiers to learn more information in limited datasets and thus improve the performance of the models. In this paper, we proposed a GNPI model to better learn the ...

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