期刊论文

Ou-Yang, L.

英文

Computational and Structural Biotechnology Journal

2001-0370

2023

21

974-990

10.1016/j.csbj.2023.01.017

This work is supported in part by funds from the National Natural Science Foundation of China [ 62173235 , 61602309 , 12271198 , 11871026 ], Guangdong Basic and Applied Basic Research Foundation [ 2022A1515010146,2019A1515011384 ], and the (Key) Project of Department of Education of Guangdong Province [No. 2022ZDZX1022 ].

本校为其他机构

Cancer is a complex disease caused primarily by genetic variants. Reconstructing gene networks within tumors is essential for understanding the functional regulatory mechanisms of carcinogenesis. Advances in high-throughput sequencing technologies have provided tremendous opportunities for inferring gene networks via computational approaches. However, due to the heterogeneity of the same cancer type and the similarities between different cancer types, it remains a challenge to systematically investigate the commonalities and specificities between gene networks of different cancer types, which ...