期刊论文

Xiao, Yi

英文

Nucleic Acids Research

0305-1048

2017

45

11

6299-6309

10.1093/nar/gkx386

NSFC [11374113, 31570722]. Funding for open access charge: NSFC [11374113, 31570722].

本校为其他机构

Direct coupling analysis of nucleotide coevolution provides a novel approach to identify which nucleotides in an RNA molecule are likely in direct contact, and this information obtained from sequence only can be used to predict RNA 3D structures with much improved accuracy. Here we present an efficient method that incorporates this information into currentRNA3D structure predictionmethods, specifically 3dRNA. Our method makes much more accurate RNA 3D structure prediction than the original 3dRNA as well as other existing prediction methods that...