Glucose Oxidase-Integrated Metal-Organic Framework Hybrids as Biomimetic Cascade Nanozymes for Ultrasensitive Glucose Biosensing

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xu, Weiqing;Jiao, Lei;Yan, Hongye;Wu, Yu;Chen, Lijuan;...

通讯作者：

Zhu, Chengzhou;Lin, Yuehe

作者机构：

[Xu, Weiqing; Jiao, Lei; Yan, Hongye; Wu, Yu; Gu, Wenling; Zhu, Chengzhou] Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol, Key Lab Pesticide & Chem Biol,Minist Educ, Wuhan 430079, Hubei, Peoples R China

[Chen, Lijuan] Zhengzhou Univ, Henan Prov Peoples Hosp, Henan Key Lab Neurol Imaging, Dept Radiol, Zhengzhou 450003, Henan, Peoples R China

[Chen, Lijuan] Zhengzhou Univ, Peoples Hosp, Zhengzhou 450003, Henan, Peoples R China

[Du, Dan; Lin, Yuehe] Washington State Univ, Sch Mech & Mat Engn, Pullman, WA 99164 USA

通讯机构：

[Zhu, Chengzhou] C

[Lin, Yuehe] W

Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol, Key Lab Pesticide & Chem Biol,Minist Educ, Wuhan 430079, Hubei, Peoples R China. Washington State Univ, Sch Mech & Mat Engn, Pullman, WA 99164 USA.

语种：

英文

关键词：

Fe-MOF;nanozymes;cascade reactions;colorimetric biosensing;glucose detection

期刊：

ACS Applied Materials & Interfaces

ISSN：

1944-8244

年：

2019

卷：

期：

页码：

22096-22101

DOI：

10.1021/acsami.9b03004

基金类别：

Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU19QN066]; Program of Introducing Talents of Discipline to Universities of China (111 program) [B17019]; Recruitment Program of Global Youth Experts of China

机构署名：

本校为第一且通讯机构

院系归属：

化学学院

摘要：

Nanozyme/natural enzyme hybrid plays a vital role in biosensing, therapy, and catalysis owing to the integrated advantages in the selectivity of natural enzymes and controllable catalytic activity of nanozymes. Herein, Fe-MIL-88B-NH2 [(Fe-metal-organic framework (MOF)] with remarkable peroxidase-like activity, ultrahigh stability, and high biocompatibility was utilized for immobilization of glucose oxidase (GOx) via an amidation coupling reaction. On the basis of the excellent selectivity and catalytic activity of Fe-MOF-GOx, a cascade catalysi...

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Glucose Oxidase-Integrated Metal-Organic Framework Hybrids as Biomimetic Cascade Nanozymes for Ultrasensitive Glucose Biosensing

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