Chiral fungicides have been widely used for disease control in agricultural cultivation due to their advantages of high efficiency, low toxicity, high selectivity, and low residue. However, the enantiomers of chiral fungicides in the chiral environment often exhibit different physiological and biochemical properties and sometimes even diametrically opposite effects. This work modified the chiral alanine-functionalized pillar[5]arene within PET nanochannels. The binary hybridized nanochannel exhibits high selectivity for the chiral fungicide Propranolol, with a selectivity coefficient of 7.36, ...