期刊论文

Raikhel, Alexander S.

英文

Journal of Biological Chemistry

0021-9258

2017

292

24

10306-10315

10.1074/jbc.M116.761387

National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [R01 AI036959]; China Scholarship Council of Chinese Ministry of Education [201506775010]; NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of Allergy & Infectious Diseases (NIAID) [R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959, R01AI036959] Funding Source: NIH RePORTER

本校为其他机构

Juvenile hormone (JH) controls many biological activities in insects, including development, metamorphosis, and reproduction. In the Aedes aegypti mosquito, a vector of dengue, yellow fever, chikungunya, and zika viruses, the metabolic tissue (the fat body, which is an analogue of the vertebrate liver) produces yolk proteins for developing oocytes. JH is important for the fat body to acquire competence for yolk protein production. However, the molecular mechanisms of how JH promotes mosquito reproduction are not completely understood. In this study we show that stimulation of the JH receptor m...