Engineered Zinc Titanate Coatings on the Titanium Surface with Enhanced Antitumor Properties and Biocompatibility

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Meng;Gong, Zheni;Zhang, Jiting;Cheng, Haoyan;Chen, Jisheng;...

通讯作者：

Zhu, Zhihong;Wan, Ying

作者机构：

[Gong, Zheni; Zhang, Jiting; Zhu, Zhihong; Zhang, Meng; Chen, Jisheng] Cent China Normal Univ, Coll Phys Sci & Technol, Inst Nanosci & Nanotechnol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.

[Cheng, Haoyan] Henan Univ Sci & Technol, Coll Mat Sci & Engn, 263 Kaiyuan Rd, Luoyang 471023, Peoples R China.

[Zeng, Yan] Cent China Normal Univ, Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.

[Wan, Ying] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, 1037 Luoyu Rd, Wuhan 430074, Hubei, Peoples R China.

通讯机构：

[Zhu, Zhihong] C

[Wan, Ying] H

Cent China Normal Univ, Coll Phys Sci & Technol, Inst Nanosci & Nanotechnol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.

Huazhong Univ Sci & Technol, Coll Life Sci & Technol, 1037 Luoyu Rd, Wuhan 430074, Hubei, Peoples R China.

语种：

英文

关键词：

zinc titanate nanogridding;anti-osteosarcoma;biocompatibility

期刊：

ACS BIOMATERIALS SCIENCE & ENGINEERING

ISSN：

2373-9878

年：

2019

卷：

期：

页码：

5935-5946

DOI：

10.1021/acsbiomaterials.9b00841

基金类别：

National Key Ramp;D Program of China [2016YFC1100100]; self-determined research funds of CCNU from the colleges' basic research and operation of MOE [CCNU19TS038, 2019QN017]

机构署名：

本校为第一且通讯机构

院系归属：

物理科学与技术学院

化学学院

摘要：

Surgical treatment of osteosarcoma is usually difficult to radically eliminate cancer cells, and it will concomitantly result in bone defects with varied sizes. To prevent tumor recurrence and reconstruction of the bone defect, there is a pressing need to develop suitable implants that have anticancer capability while promoting the regeneration of bone tissues. Here, we first report the design and fabrication of titanium-based implants engineered with a series of alveolate double-layered zinc titanate nanogridding coatings (NG-Zn0.01, NG-Zn0.05...

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Engineered Zinc Titanate Coatings on the Titanium Surface with Enhanced Antitumor Properties and Biocompatibility

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