National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [20872043]; Academic Leaders in Wuhan Municipality [200851430486]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
The scope of the novel ruthenium-catalyzed tandem cross-metathesis/ intramolecular-hydroarylation sequence is described. This methodology offers a practical and efficient synthesis of structurally diverse and complex tetrahydrocarbazoles in good to excellent yields (up to 98%). Moreover, preliminary efforts towards the development of an enantioselective version of the current process by sequential catalysis with ruthenium complex and chiral amine are presented, with high yields and enantioselectivities (up to 88% yield an...