Engineering a NO-Regulated Nanofluidic Sensor through the Cyclization Reaction Strategy

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成果类型：

期刊论文

作者：

Han, Yunfeng;Sun, Zhongyue;Sun, Ziyan;Chen, Xiaoya;Zhang, Yongxue*;...

通讯作者：

Zhang, Yongxue;Sun, Yao;Li, Haibing

作者机构：

[Han, Yunfeng; Zhang, Yongxue] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Nucl Med, Wuhan 430022, Peoples R China.

[Han, Yunfeng] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Nucl Med, Wuhan 430030, Peoples R China.

[Li, Haibing; Sun, Zhongyue; Chen, Xiaoya; Sun, Yao; Sun, Ziyan; Li, HB] Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.

[Sun, Zhongyue] Hubei Univ Chinese Med, Sch Lab Med, Wuhan 430065, Peoples R China.

[Sun, Ziyan] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Radiol, Wuhan 430030, Peoples R China.

通讯机构：

[Zhang, Yongxue] H

[Sun, Y; Li, HB] C

Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Nucl Med, Wuhan 430022, Peoples R China.

Cent China Normal Univ, Coll Chem, Key Lab Pesticides & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.

语种：

英文

关键词：

cyclization reactions;ion rectification;nanochannel;nanosensors;nitic oxide

期刊：

CHEMISTRY-A EUROPEAN JOURNAL

ISSN：

0947-6539

年：

2020

卷：

期：

页码：

11099-11103

DOI：

10.1002/chem.202001089

基金类别：

National Key Research and Development Program of China [2018YFD0200102]; NSFCNational Natural Science Foundation of China [21708012, 21772055, 21572076]; Wuhan scientific and technological projects [2019020701011441]; NSFHPNational Science Foundation (NSF) [2017CFB151]; Self-determined research funds of CCNU from the colleges basic research and operation of MOE

机构署名：

本校为通讯机构

院系归属：

化学学院

摘要：

Nitric oxide (NO) is known to be a secondary in vivo signaling agent, demonstrating various biological functions through regulating ion flux in channels. Considering the crucial role of NO in vivo, herein, a biomimetic NO-regulated nanofluidic sensor has been fabricated through a cyclization reaction strategy. This nanofluidic sensor exhibited a promising NO selectivity, sensitivity, and non-interference performance in complex matrices. Thus, such a NO-driven nanosensor will be meaningful for scientific researchers to grasp the in vi...

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Engineering a NO-Regulated Nanofluidic Sensor through the Cyclization Reaction Strategy

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