The title compound, C33H28IN5O 6, is a molecular clip based on the glycoluril framework. A 4-pyridinylethynyl-substituted benzene ring is fused to one seven-membered ring, which binds two of the N atoms from separate rings of the glycoluril system. The second, similar, seven-membered ring is fused to an iodobenzene ring. The orientation of these fused-benzenering substituents is trans with respect to the glycouril framework. The crystal structure is stabilized by weak C - H⋯O and C - H⋯N hydrogen bonds and C - H⋯π interactions. ...