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Comorbidity between depression and asthma via immune-inflammatory pathways: A meta-analysis

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成果类型:
期刊论文
作者:
Jiang, Mingdi;Qin, Ping;Yang, Xu*
通讯作者:
Yang, Xu
作者机构:
[Yang, Xu; Jiang, Mingdi] Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Sect Environm Biomed, Wuhan 430079, Peoples R China.
[Qin, Ping] Univ Oslo, Natl Ctr Suicide Res & Prevent, Inst Clin Med, Oslo, Norway.
[Yang, Xu] Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Sect Environm Biomed, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
通讯机构:
[Yang, Xu] C
Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Sect Environm Biomed, Bldg 5,152 Luo Yu Rd, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Allergy;Asthma;Cytokines;Depression
期刊:
Journal of Affective Disorders
ISSN:
0165-0327
年:
2014
卷:
166
页码:
22-29
基金类别:
In summary, our analyses have indicated that people with depression is 3.17 times likely to have a comorbidity of asthma compared with that of counterparts without depression, and that patients with asthma is 1.52 times like to have a comorbid depression compared with those without asthma. At the same time, our results have shown significant differences in concentration of certain cytokines in depressed individuals as compared to those without depression, suggesting that allergy related
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Background: Depression is often present in patients with asthma and vice versa. In this review, we aimed to summarize reports on the comorbidity of depression and asthma, and to seek evidence that the biological mechanisms of allergy may have an important role linking asthma and depression. Method: To explore the relationship and pathway underpinning this comorbidity, we reviewed medical articles and undertook a meta-analysis of epidemiological studies on (i) incidence of asthma in patients with depression; (ii) morbidity of depression in patients with asthma; (iii) concentration of cytokines ...

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