[叶染枫; 刘旭东; 李慧; 杨旭; 闵安娜; 张玉超; 陈明清; 刘锋明; 赵莉琴] Laboratory of Environmental Science, College of Life Sciences, Huazhong Normal University, Wuhan 430079, China
通讯机构:
Laboratory of Environmental Science, College of Life Sciences, Huazhong Normal University, China
To investigate the oxidative damage of brain and the effects on learning and memory ability induced by butylbenzyl phthalate (BBP) in mice. Twenty-four male Kun Ming (KM) mice were randomly assigned into 4 groups (n=6), exposed to different concentrations of BBP (0, 50, 250 and 1250 mg/kg) by oral gavage for fourteen days. During the exposure period, the Morris water maze was used to test the learning and memory abilities. After Morris water maze test the experimental animals were ended lives, and then the reactive oxygen species (ROS) level, malondialdehyde (MDA) and glutathione (GSH) content...