期刊论文

Mingqing Chen

英文

Food and Chemical Toxicology

0278-6915

2023

173

113642

10.1016/j.fct.2023.113642

CRediT authorship contribution statement Yunyi Wang: Investigation, Validation, Methodology, Data curation, Writing – original draft. Zhaolan Wei: Investigation, Methodology, Conceptualization. Ke Xu: Validation. Xuan Wang: Investigation. Xiao Gao: Investigation. Qi Han: Investigation. Shuwei Wang: Visualization, Software. Mingqing Chen: Conceptualization, Methodology, Writing – review & editing, Project administration, acquisition, Supervision. Acknowledgements This work was supported by the National Natural Science Foundation of China (42277437), Fundamental Research Funds for the Central Universities (CCNU20TS020), CCNU Graduate Education Innovation Project (2022CXZZ084).

本校为第一机构

Nanoplastics have become ubiquitous in the global environment and have attracted increasing attention. However, whether there is an influence between exposure to nanoplastics and diabetes is unclear. To determine the effects of exposure to Polystyrene nanoplastics (PS-NPs) and evaluate the underlying mechanisms, mice were orally exposed to PS-NPs at dosages of 1, 10, 30 mg/kg/day for 8 weeks, alone or combined with a high fat diet and streptozocin (STZ) injection. Our data showed that exposure to 30 mg/kg/day PS-NPs alone induced a significant ...