期刊论文

Wu, An-Xin（吴安心）;Jia, Feng-Cheng

英文

Organic Letters

1523-7060

2018

20

14

4231-4234

10.1021/acs.orglett.8b01645

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472056, 21602070, 21772051]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU15ZX002, CCNU16A05002]; 111 ProjectMinistry of Education, China - 111 Project [B17019]

本校为第一且通讯机构

An efficient transition-metal-free oxidative cyclization reaction using isatins and alkynes for the facile synthesis of structurally diverse 4-quinolones has been developed. Intriguingly, switchable access to substituted 3-carboxylate-4-quinolones and 1-vinyl-3-carboxylate-4-quinolones could be achieved by choosing a different base in the reaction. The obtained products could undergo further transformations, increasing the applica...