期刊论文

Huang Ming-Zhi

中文

有机化学

0253-2786

2006

26

11

1539-1543

10.3321/j.issn:0253-2786.2006.11.011

国家自然科学基金（No．20372021）资助项目．；

本校为第一且通讯机构

为了寻找高效、安全的除草活性化合物, 合成了12个全新的N-{2-氯-5-[3-甲基-2,6-二氧-4-三氟甲基-2,3-二氢嘧啶-1(6H)-基]苯基}酰胺类化合物, 其化学结构经IR, ~1H NMR, LC/MS和元素分析确证. 初步生物活性测定结果表明, 该类化合物具有一定的除草活性, 如7a, 7b, 7c, 7g, 7h, 7i, 7k和7l在有效成分75 g/hm~2剂量下, 茎叶处理对苘麻(Abutilon theophrasti)、刺苋(Amaranthus spinosus)等阔叶杂草具有良好的除草活性, 其抑制率达100%.

In search of safer and more efficacious herbicidal compounds, twelve N-{2-chloro-5-[3-methyl-2,6-dioxo-4-trifluoromethyl-2,3-dihydropyrimidin-1(6H) -yl]phenyl} amides were synthesized. Their structures were confirmed by IR, 1H NMR, LC/MS spectra and elemental analysis. Preliminary bioassay showed that most of title compounds had good herbicidal activity, for example, 7a, 7b, 7c, 7g, 7h, 7i, 7k and 7l exhibited 100% inhibition to broad-leaved weeds, such as Abutilon theoph...