期刊论文

Ding Mingwu

中文

有机化学

0253-2786

2016

36

7

1662-1667

10.6023/cjoc201601026

国家自然科学基金

本校为第一且通讯机构

提出了一种利用连续Staudinger/aza-Wittig反应合成新稠环系12H,14H-喹唑啉并[3,4-a]-3,1-苯并噁嗪的方法.该方法应用叠氮化物3与三苯基膦、酰氯或CS_2的连续Staudinger/aza-Wittig/成环反应,以良好的产率生成12H,14H-喹唑啉并[3,4-a]-3,l-苯并噁嗪5或6.

A one-pot synthetic approach to new fused heterocyclic skeleton 12H,14H-quinazolino[3,4-a]-3,1-benzoxazine by Staudinger/aza-Wittig sequence has been developed. The sequential reaction of azides 3 with triphenylphosphine and acyl chlorides or CS 2 produced 12H,14H-quinazolino[3,4-a]-3,1-benzoxazines 5 or 6 in good yields via a consecutive Staudinger/aza-Wittig/ cyclization react...