期刊论文

Recent Developments of Reactions with C,N-Cyclic Azomethine Imines

Yang Qingqing;Xiao Wengjing

中文

有机化学

0253-2786

2020

40

11

3559-3595

10.6023/cjoc202006072

* Corresponding authors. E-mail: qingqing_yang@ctgu.edu.cn; wxiao@mail.ccnu.edu.cn Received June 30, 2020; revised September 4, 2020; published online September 15, 2020. Dedicated to the 40th anniversary of Chinese Journal of Organic Chemistry Project supported by the National Natural Science Foundation of China (No. 21702121), the Open Fund from Hubei Key Laboratory of Natural Products Re-search and Development (China Three Gorges University) (No. NPRD-2018010), the Research Fund for Excellent Dissertation of China Three Gorges Uni-versity and the Programme of Introducing Talents of Discipline to Universities (111 Project, No. D20015). 国家自然科学基金(No. 21702121)、三峡大学天然产物研究与利用湖北重点实验室开放基金(No. NPRD-2018010)、三峡大学学位论文培优基金和高等 学校学科创新引智计划(111 计划, No. D20015)资助项目.

本校为通讯机构

在环状偶氮次甲基亚胺类1,3-偶极子中,C,N-环状偶氮次甲基亚胺是使用最广泛的反应试剂,用于结构多样化的四氢异喹啉衍生物的构建.简单综述了C,N-环状偶氮次甲基亚胺参与的反应研究进展,重点介绍[3+2]、[3+3]、[3+4]、[5+1]、[3+1]环加成以及其他反应,并讨论了反应的特点、反应过程及合成应用,最后展望了它的发展前景.

Among various 1,3-dipoles of cyclic azomethine imines, C,N-cyclic azomethine imines are the most widely used reagents in the construction of diverse tetrahydroisoquinoline derivatives. The developments of reactions with C,N-cyclic azomethine imines including [3+2], [3+3], [3+4], [5+1], [3+1] cycloaddition reactions and miscellaneous reactions are summarized. The properties of reactions, reaction processes and synthetic applications are discussed. Finally, the pr...