* Corresponding authors. E-mail: chenjiarong@mail.ccnu.edu.cn; wxiao@mail.ccnu.edu.cn Received July 1, 2020; revised August 1, 2020; published online August 11, 2020. Dedicated to the 40th anniversary of Chinese Journal of Organic Chemistry. Project supported by the National Natural Science Foundation of China (Nos. 21820102003, 91956201). 国家自然科学基金(Nos. 21820102003, 91956201)资助项目. † 共同第一作者(These authors contributed equally to this work).
Cinchona alkaloids widely exist in nature, which have attracted extensive interest of researchers because of their readily availability, biological activity, unique structural properties, and easy modification. With the development of asymmetric synthetic chemistry, cinchona alkaloids and their derivatives have been used as a privileged class of chiral catalysts or ligands in many catalytic asymmetric reactions. In particular, a variety of cinchona alkaloid-derived chiral catalysts and ligands have been developed and applied by organic chemists...