A new near-infrared (NIR) fluorescent turn-on probe (CDCI-CO) based on a novel coumarin-dicyanoisophorone hybrid fluorophore for detection of CO both in vitro and in vivo was reported. By applying Tsuji-Trost reaction to remove the allylcarbonate group, this probe exhibits excellent capability of detecting CO in aqueous solution with rapid response, high selectivity and sensitivity, distinct NIR fluorescent turn-on signal changes at 710 nm, and a remarkable large Stokes shift of 222 nm. The detection limit of this probe for CO was determined to...
