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Reproductive toxicity of dibutyl phthalate adsorbed on carbon nanotubes in male Balb/C mice

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成果类型:
期刊论文
作者:
Ye, Xin;Zhou, Tingting;Qin, Yujie;He, Suli;Zhang, Hongmao;...
通讯作者:
Hongmao Zhang<&wdkj&>Shumao Ding
作者机构:
[Ye, Xin] Sichuan Univ Sci & Engn, Coll Bioengn, Liquor Marking Biol Technol & Applicat Key Lab Sic, Yibin, Peoples R China.
[Zhou, Tingting; Qin, Yujie; He, Suli; Zhang, Hongmao; Ding, Shumao] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Hubei, Peoples R China.
通讯机构:
[Hongmao Zhang; Shumao Ding] H
Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Hubei, China
语种:
英文
关键词:
Carbon nanotubes;Compound exposure;Dibutyl phthalate;Reproductive toxicity
期刊:
Reproductive Toxicology
ISSN:
0890-6238
年:
2022
卷:
110
页码:
180-187
基金类别:
This research was funded by the National Natural Science Foundation of China (General Program) (No. 31772471).
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Dibutyl phthalate (DBP) is an environmental hormone disrupter. This study was designed to investigate whether DBP adsorbed in multi-walled carbon nanotubes (MWCNTs) can easily cross the blood-testis barrier and slow down the degradation of DBP in male mice, thereby prolonging the interference effect of DBP. The results showed that: in male Balb/C mice, the sperm density of the MWCNTs group and the DBP plus MWCNTs group decreased significantly (p < 0.05); and the sperm deformity rate increased significantly (p < 0.05). Testicular tissue sections...

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