期刊论文

Biosynthesis of arabinogalactan (AG) polysaccharides of arabinogalactan-proteins in plants

Xu, W.-L.

中文

植物生理与分子生物学学报

1671-3877

2018

54

8

1263-1271

10.13592/j.cnki.ppj.2018.0088

31671735:国家自然科学基金 31371234:国家自然科学基金 31601350:国家自然科学基金 2016CFA071:湖北省自然科学基金 CCNU18TS021:中央高校基本科研业务费专项

本校为第一且通讯机构

阿拉伯半乳聚糖蛋白（arabinogalactan-proteins,AGPs）是一类高度糖基化的富含羟脯氨酸（hydroxyproline,Hyp）的糖蛋白,广泛分布于植物的细胞壁、质膜和胞外分泌物中,在植物生长和发育的多个过程中发挥重要作用。主要进行两种翻译后修饰,首先通过脯氨酸羟化酶催化的脯氨酸羟基化,随后在一些羟脯氨酸的羟基上添加阿拉伯半乳聚糖（arabinogalactan,AG）,以AG为主的多糖可占到AGP分子量的90%,这意味着多糖链主要决定着AGP与其他分子间的相互作用进而影响其功能。从2010年2个能特异糖基化AGP的糖基转移酶At FUT4和At FUT6被鉴定以来,越来越多参与AGP多糖合成的糖基转移酶被鉴定。本文综述了近10年...

Arabinogalactan-proteins (AGPs) are highly glycosylated hydroxyproline (Hyp)-rich glycoproteins. They are widely distributed in cell walls, plasma membranes and extracellular secretions of plants and play important roles in various processes of plant growth and development. These proteins undergo extensive posttranslational modification, which includes the conversion of proline (Pro) residues to hydroxyproline (Hyp) and subsequent addition of arabinogalactan (AG) polysaccharides to Hyp residues. Given that the carbohydrate moieties typically ac...