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A CTL - Lys immune function maintains insect metamorphosis by preventing gut bacterial dysbiosis and limiting opportunistic infections

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成果类型:
期刊论文
作者:
Xiong, Pei;Wang, Wen-Wen;Liu, Xu-Sheng;Wang, Yu-Feng;Wang, Jia-Lin
通讯作者:
Wang, JL
作者机构:
[Wang, Wen-Wen; Xiong, Pei; Liu, Xu-Sheng; Wang, JL; Wang, Jia-Lin; Wang, Yu-Feng] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Wang, JL ] C
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Pupariation;Lipid metabolism;Ecdysone;C-type lectin;Lysozyme
期刊:
BMC Biology
ISSN:
1741-7007
年:
2024
卷:
22
期:
1
页码:
1-17
基金类别:
This work was supported by grants from the National Natural Science Foundation of China (31872301 and 32172489) and the Guizi Young Scholar Program of Central China Normal University (2022).
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Gut bacteria are beneficial to the host, many of which must be passed on to host offspring. During metamorphosis, the midgut of holometabolous insects undergoes histolysis and remodeling, and thus risks losing gut bacteria. Strategies employed by holometabolous insects to minimize this risk are obscure. How gut bacteria affect host insects after entering the hemocoel and causing opportunistic infections remains largely elusive. We used holometabolous Helicoverpa armigera as a model and found low Lactobacillus load, high level of a C-type lectin...

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