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Facile Synthesis of 3-Substituted Isoquinolines Derivatives via Microwave-assisted Tandem Three-component Coupling Cyclization

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成果类型:
期刊论文
作者:
Lin Long;Wu Qiongyou*;Huang Shaowei;Yang Guangfu(杨光富
通讯作者:
Wu Qiongyou
作者机构:
[Yang Guangfu; Huang Shaowei; Lin Long; Wu Qiongyou] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Wu Qiongyou] C
Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
关键词:
palladium/copper-catalyst;microwave;isoquinolines;tandem reaction;coupling cyclization
关键词(中文):
喹啉衍生物;微波辅助;三组分;合成;环化;偶联;串联;末端炔烃
期刊:
中国化学
ISSN:
1001-604X
年:
2012
卷:
30
期:
5
页码:
1075-1082
基金类别:
Acknowledgement This work was supported by the National Natural Science Foundation of China (No. 21002038) and the Self-determined Research Funds of CCNU from the Colleges' Basic Research and Operation of MOE (No. CCNU09A01014).
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A novel three-component reaction of o-bromobenzaldehyde, terminal alkynes and tert-butyl amine has been established, which proceeded smoothly to give 3-substituted isoquinolines in good yields in the presence of palladium/copper catalyst...
摘要(中文):
o-bromobenzaldehyde,终端炔属羟和 tert 丁基胺的新奇三部件的反应被建立了,它顺利继续了在微波照耀下面面对钯 / 铜催化剂在好收益给 3 代用品 isoquinolines。

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