A concise construction of 12H-benzo[4,5]thiazolo[2,3-b]quinazolin-12-ones via an unusual TBHP/Na2CO3 promoted cascade oxidative cyclization and interrupted Dimroth rearrangement
National Natural Science Foundation of China [21472056, 21602070]; Fundamental Research Funds for the Central Universities [CCNU15ZX002, CCNU16A05002]; Central China Normal University [2016CXZZ67]
机构署名：
本校为第一且通讯机构
院系归属：
化学学院
摘要：
An efficient transition-metal-free cascade reaction has been developed for the facile synthesis of 12H-benzo[4,5]thiazolo[2,3-b]quinazolin-12-one derivatives from commercially available isatins and 2-haloaryl isothiocyanates. A preliminary mechanistic study suggested an interrupted Dimroth rearrangement was the key...
