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The hippocampus may be more susceptible to environmental noise than the auditory cortex

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成果类型:
期刊论文
作者:
Cheng, Liang;Wang, Shao-Hui;Huang, Yun;Liao, Xiao-Mei*
通讯作者:
Liao, Xiao-Mei
作者机构:
[Wang, Shao-Hui; Liao, Xiao-Mei; Cheng, Liang] Cent China Normal Univ, Sch Life Sci, Luoyu Rd 152, Wuhan 430079, Hubei Province, Peoples R China.
[Wang, Shao-Hui; Liao, Xiao-Mei; Cheng, Liang] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei Province, Peoples R China.
[Huang, Yun; Cheng, Liang] Cent China Normal Univ, Minist Educ, Key Lab Adolescent Cyberpsycol & Behav CCNU, Wuhan 430079, Hubei Province, Peoples R China.
[Huang, Yun; Cheng, Liang] Cent China Normal Univ, Sch Psychol, Wuhan 430079, Hubei Province, Peoples R China.
通讯机构:
[Liao, Xiao-Mei] C
Cent China Normal Univ, Sch Life Sci, Luoyu Rd 152, Wuhan 430079, Hubei Province, Peoples R China.
语种:
英文
关键词:
Auditory cortex;Hippocampus;Noise exposure;Oxidation;Tau phosphorylation
期刊:
Hearing Research
ISSN:
0378-5955
年:
2016
卷:
333
页码:
93-97
基金类别:
National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31300914]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2013M531719, 2014T70716]; Fundamental Research Funds for Central UniversitiesFundamental Research Funds for the Central Universities [CCNU14A05046, CCNU15A02024, CCNU15A02029]; Key Laboratory of Adolescent Cyberpsycology and Behavior of Ministry of Education, Central China Normal University [2014B10]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
心理学院
摘要:
Noise exposure can cause structural and functional problem in the auditory cortex (AC) and hippo campus, the two brain regions in the auditory and non-auditory systems respectively. The aim of the present study was to explore which one of these two brain regions may be more susceptible to environmental noise. The AC and hippocampus of mice were separated following 1 or 3 weeks exposure to moderate noise (80 dB SPL, 2 h/day). The levels of oxidative stress and tau phosphorylation were then measured to evaluate the effects by noise. Results showed significant peroxidation and tau hyperphosphoryl...

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