5mC-Related lncRNAs as Potential Prognostic Biomarkers in Colon Adenocarcinoma

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成果类型：

期刊论文

作者：

Huang, Yinghui;Huang, Huiqian;Wang, Yong;Liu, Hui;Huang, Yingdan

通讯作者：

Liu, H;Huang, YD

作者机构：

[Huang, Yinghui; Liu, Hui] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan 430056, Peoples R China.

[Huang, Yinghui; Liu, Hui] Cent China Normal Univ, Sch Psychol, Wuhan 430056, Peoples R China.

[Huang, Huiqian] Cent China Normal Univ, Natl Res Ctr Cultural Ind, Wuhan 430056, Peoples R China.

[Wang, Yong] Nanchang Univ, Dept Med Oncol, Affiliated Hosp 1, 17 YongwaiZhengRd, Nanchang 330209, Jiangxi, Peoples R China.

[Huang, Yingdan; Huang, YD] Huazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Dept Lymphoma Med, Wuhan 430079, Peoples R China.

通讯机构：

[Huang, YD ] H

[Liu, H ] M

Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan 430056, Peoples R China.

Cent China Normal Univ, Sch Psychol, Wuhan 430056, Peoples R China.

Huazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Dept Lymphoma Med, Wuhan 430079, Peoples R China.

语种：

英文

关键词：

5-methylcytosine;Colon adenocarcinoma;Immunotherapy;LncRNA signature;Prognosis

期刊：

Biology

ISSN：

2079-7737

年：

2022

卷：

期：

DOI：

10.3390/biology11020231

基金类别：

Funding: This study was supported by the Collaborative Innovation Center for Informatization and Balanced Development of K-12 Education by MOE and Hubei Province (Grant number xtzd2021-013) and the Graduate Student Innovation Special Fund Project of Jiangxi Province (No.YC2021-B039).

机构署名：

本校为通讯机构

院系归属：

心理学院

国家文化产业研究中心

摘要：

Globally, colon adenocarcinoma (COAD) is one of the most frequent types of malignant tumors. About 40~50% of patients with advanced colon adenocarcinoma die from recurrence and metastasis. Long non-coding RNAs (lncRNAs) and 5-methylcytosine (5mC) regulatory genes have been demonstrated to involve in the progression and prognosis of COAD. The goal of this study was to explore the biological characteristics and potential predictive value of 5mC-related lncRNA signature in COAD. In this research, The Cancer Genome Atlas (TCGA) was utilized to obta...

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5mC-Related lncRNAs as Potential Prognostic Biomarkers in Colon Adenocarcinoma

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