Guest-Induced Planar-Chiral Pillar[5]arene Surface for Selectively Adsorbing Protein Based on Host-Guest Chemistry

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Guang;Gong, Wen;Yang, Lei;Cheng, Ming;Yan, Hewei;...

通讯作者：

Li, Haibing;Lu, Zhiyan;Zhang, Fan;Quan, Jiaxin

作者机构：

[Cheng, Ming; Li, Guang; Yang, Lei; Li, Haibing; Yan, Hewei] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.

[Gong, Wen] Hosp Hubei Prov, Peoples Hosp Hubei Prov 3, Dept Cardiol, Wuhan 430030, Peoples R China.

[Lu, Zhiyan] Wuhan Univ, Zhongnan Hosp, Dept Forens Med, Wuhan 430071, Peoples R China.

[Zhang, Fan] Hubei Univ, Coll Chem & Chem Engn, Hubei Collaborat Innovat Ctr Adv Organ Chem Mat, Minist Educ,Key Lab Synth & Applicat Organ Funct, Wuhan 430062, Peoples R China.

[Quan, Jiaxin] Hanjiang Normal Univ, Dept Chem & Environm Engn, Shiyan 442000, Peoples R China.

通讯机构：

[Li, Haibing] C

[Lu, Zhiyan] W

[Zhang, Fan; Quan, Jiaxin] H

Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.

Wuhan Univ, Zhongnan Hosp, Dept Forens Med, Wuhan 430071, Peoples R China.

语种：

英文

期刊：

Bioconjugate Chemistry

ISSN：

1043-1802

年：

2022

卷：

期：

页码：

2237-2244

DOI：

10.1021/acs.bioconjchem.1c00527

基金类别：

National Key Research and Development Program [2021YFA0716702]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [22071074, 21772055, 21904031]; 111 ProjectMinistry of Education, China - 111 Project [B17019]; Open Project Program of State Key Laboratory of Food Science and Technology, Jiangnan University [SKLF-KF-202103]; self-determined research funds of CCNU from the colleges' basic research and operation of MOE

机构署名：

本校为第一且通讯机构

院系归属：

化学学院

摘要：

In living systems, the adsorption of a protein on biointerfaces is a universal phenomenon, such as the specific binding of an antibody and antigen, which plays an important role in body growth and life maintenance. The exploration of a protein-selective adsorption on the biointerface is of great significance for understanding the life process and treatment in vitro. Herein, on the basis of biomimetic strategies, we fabricated a planar-chiral NH2-pillar[5]arene modified silicon surface (pR-/pS-NP5 surfaces) for a highly enantioselective adsorpti...

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Guest-Induced Planar-Chiral Pillar[5]arene Surface for Selectively Adsorbing Protein Based on Host-Guest Chemistry

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