Mitochondrial responses and changes of calcium ions in apoptotic insect SL-1 cells induced by Syngrapha falcifera multiple nuclear polyhedrosis virus (SfaMNPV) are reported in this paper. By using Rhodamine 123 as a fluorescent labeling probe, flow cytometry analysis and confocal laser scanning microscope observation we observed that the mitochondrial transmembrane potential (ΔΨm) began to decrease in SL-1 cells at 4 h post infection and Δψm reduced continuously with the extension of virus infection. Western blotting indicated that the Bcl-...