期刊论文

Neuroscientists are questing to unlock the secrets of three-dimensional navigation in the brains of bats

Chen, Q.

中文

科学通报

0023-074X

2020

65

8

656-664

10.1360/TB-2019-0404

31200832:国家自然科学基金 31772454:国家自然科学基金 CCNU19GF007:中央高校基本科研业务费专项

本校为第一且通讯机构

揭开人和动物大脑方位感知与空间导航的秘密,一直是一个令人着迷的问题.科学家通过对大鼠和蝙蝠等动物近50年的研究,使我们对大脑二维（2 dimension, 2D）导航的神经基础有了较清楚的认识.研究发现,在海马和内嗅皮质等脑区有专门的导航细胞,包括位置细胞、网格细胞、边界细胞、头朝向细胞等.这些细胞及它们的"细胞域"可为2D空间导航提供"空间认知地图"或"心灵环境地图"和"指南针".然而,人和大量动物都生活在三维（3 dimension, 3D）空间中,大脑如何完成3D空间环境下的定位和导航?近年来,通过对爬行和飞行状态蝙蝠的研究,发现参与2D导航的那些细胞在3D空间下反应特性和模式均发生明显变化;蝙蝠属...

Unlocking the secrets of spatial orientation and navigation in the brains of humans and animals is a fascinating challenge question. Over the past 50 years, studying the brains of rats, bats, and other animals have provided insights into the neural basis of two dimensional (2D) navigation. Cells exist in the brain that direct navigation, including place, grid, border and head-direction cells. The fields of these cells provide cognitive maps (i.e., a unified representation of the spatial environment) and compass, which regulate 2D navigation. Pl...