A new near-infrared (NIR) fluorescent probe was developed for the detection of CO in living systems. This probe is based on a unique cyanine fluorophore and uses an allyl ether moiety as the reaction site. Optical studies in solution show that this probe has good water solubility and possesses desirable sensing properties for CO including rapid response, high selectivity and sensitivity, large Stokes shift (123 nm), distinct colorimetric changes, and significant turn-on NIR fluorescence changes at 715 nm with high signal-to-noise ratio. Ratiometric fluorescent detection of CO with this probe a...
