Illumination with 630 nm Red Light Reduces Oxidative Stress and Restores Memory by Photo-Activating Catalase and Formaldehyde Dehydrogenase in SAMP8 Mice

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Jingnan;Yue, Xiangpei;Luo, Hongjun;Jiang, Wenjing;Mei, Yufei;...

通讯作者：

He, Rongqiao;Jia, Jianping;Lyu, Jihui;Luo, Wenhong;Tong, Zhiqian

作者机构：

[Lyu, Jihui; Yue, Xiangpei; He, Rongqiao; Jia, Jianping; Jiang, Wenjing; Mei, Yufei; Zhang, Jingnan; Tong, Zhiqian; Ai, Li; He, RQ; Jia, JP; Lyu, JH] Capital Med Univ, Lab Alzheimers Optoelect Therapy, Alzheimers Dis Ctr, Beijing Inst Brain Disorders,Ctr Brain Disorders, Beijing, Peoples R China.

[Lyu, Jihui; Jiang, Wenjing; Zhang, Jingnan] Beijing Geriatr Hosp, Ctr Cognit Disorders, Beijing, Peoples R China.

[Luo, Hongjun; Luo, Wenhong] Shantou Univ Med Coll, Cent Lab, Shantou, Guangdong, Peoples R China.

[Sun, Binggui; Mei, Yufei] Zhejiang Univ, Sch Basic Med Sci, Hangzhou, Zhejiang, Peoples R China.

[Yang, Hui; Gao, Ge] Capital Med Univ, Sch Basic Med Sci, Dept Neurobiol, Beijing, Peoples R China.

通讯机构：

[He, RQ; Jia, JP; Lyu, JH; Jia, Jianping; Tong, Zhiqian] C

[Lyu, Jihui] B

[Luo, Wenhong] S

[He, Rongqiao] U

Capital Med Univ, Lab Alzheimers Optoelect Therapy, Alzheimers Dis Ctr, Beijing Inst Brain Disorders,Ctr Brain Disorders, Beijing, Peoples R China.

语种：

英文

关键词：

acetylcholine;formaldehyde;hydrogen peroxide;light-emitting diode with red light;memory;oxidative stress

期刊：

ANTIOXIDANTS & REDOX SIGNALING

ISSN：

1523-0864

年：

2019

卷：

期：

页码：

1432-1449

DOI：

10.1089/ars.2018.7520

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [8153000092, 31671183]; Beijing Natural Science FoundationBeijing Natural Science Foundation [7172022]; Scientific Research Common Program of Beijing Municipal Commission of EducationBeijing Municipal Commission of Education [KM201510025014]; Major Projects Fund of Beijing Institute for Brain Disorders [ZD2015-08]; Capital Characteristic Clinic Project of the Beijing Municipal Science and Technology Commission [Z151100004015023, Z161100000217141]; MOST [2016YFC1306300]; Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZYXL201834]; Natural Scientific Foundation of CCMU [2015ZR31, 2016JS09]

机构署名：

本校为其他机构

院系归属：

生命科学学院

摘要：

Aims: Pharmacological treatments for Alzheimer's disease (AD) have not resulted in desirable clinical efficacy over 100 years. Hydrogen peroxide (H 2 O 2 ), a reactive and the most stable compound of reactive oxygen species, contributes to oxidative stress in AD patients. In this study, we designed a medical device to emit red light at 630 ± 15 nm from a light-emitting diode (LED-RL) and investigated whether the LED-RL reduces brain H 2 O 2 levels and improves memory in senescence-accelerated prone 8 mouse (SAMP8) model of age-related dementia...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Illumination with 630 nm Red Light Reduces Oxidative Stress and Restores Memory by Photo-Activating Catalase and Formaldehyde Dehydrogenase in SAMP8 Mice

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问