A liquid-phase combinatorial synthesis of N-carbonylamido-2-(4-oxo-4H-1- benzopyran-3-yl)-4-thiazolidinones derivatives was successfully performed using N′-(chromon-3-yl)methylidene hydrazide derivatives and mercaptoacetic acid as reactants. Compared to an identical library generated by conventional parallel synthesis, the microwave-assisted parallel synthesis approach dramatically decreased the reaction time from an average of 8 h to 5 min, and substantially increased the product yields. The coupling of microwave technology with liquid-phase ...
