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CuO/I-2-mediated intramolecular annulation for the synthesis of 2-aroyl-3-hydroxy-4-iodonaphthalenes

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成果类型:
期刊论文
作者:
Cai, Qun;Yang, Yan;Li, Deng-Kui;Jia, Feng-Cheng;Xu, Cheng;...
通讯作者:
Wu, An-Xin
作者机构:
[Jia, Feng-Cheng; Xu, Cheng; Cai, Qun; Yang, Yan; Wu, An-Xin; Li, Deng-Kui] Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Wu, An-Xin] C
Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
语种:
英文
期刊:
RSC Advances
ISSN:
2046-2069
年:
2015
卷:
5
期:
109
页码:
89427-89430
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472056, 21272085]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A novel strategy has been developed for the direct synthesis of 2-aroyl-3-hydroxy-4-iodonaphthalenes from easily available (Z)-2-(hetero)arylidene-1-(hetero)arylbutane-1,3-diones in the presence of copper(ii) oxide and iodine. This domino process involves consecutive methyl iodination/carbon-carbon double bond isomerization/6π-electrocyclization/aromatization/arene iodinatio...

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