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PM2.5 induced neurodegenerative-like changes in mice and the antagonistic effects of vitamin E

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成果类型:
期刊论文
作者:
Liu, Xudong;Zhang, Yuchao;Yang, Xu*
通讯作者:
Yang, Xu
作者机构:
[Yang, Xu; Zhang, Yuchao; Liu, Xudong] Moutai Inst, Dept Food Sci & Engn, Renhuai 564507, Peoples R China.
[Yang, Xu] Cent China Normal Univ, Coll Life Sci, Lab Environm Biomed, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Yang, Xu] M
[Yang, Xu] C
Moutai Inst, Dept Food Sci & Engn, Renhuai 564507, Peoples R China.
Cent China Normal Univ, Coll Life Sci, Lab Environm Biomed, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
期刊:
TOXICOLOGY RESEARCH
ISSN:
2045-452X
年:
2019
卷:
8
期:
2
页码:
172-179
基金类别:
Regular Undergraduate Institutions Nature Science Research Project of the Guizhou Education Department (Technology top-notch talent support project) [QianjiaoheKYzi[2018]083]
机构署名:
本校为通讯机构
院系归属:
生命科学学院
摘要:
Neurodegenerative diseases (ND) affect a large and ever-growing population globally, resulting in heavy burdens for patients and their families. Though some specific genes related to ND have been identified, the genetic factors fail to fully account for the pathogenesis of ND. Therefore, the roles of the environment and life styles in the occurrence of ND are being actively probed. As a typical air pollutant, exposures to PM2.5 are linked to the occurrence of ND. However, there are still few studies on this exposure, particularly on the in vivo and molecular mechanisms of the ND-like lesions a...

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