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Association of the FABP2 Ala54Thr polymorphism with type 2 diabetes, obesity, and metabolic syndrome: A population-based case-control study and a systematic meta-analysis

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成果类型:
期刊论文
作者:
Liu, Y.;Wu, G.;Han, L.;Zhao, K.;Qu, Y.;...
通讯作者:
Huang, Q.
作者机构:
[Han, L.; Wu, G.; Huang, Q.; Liu, Y.; Zhao, K.] Cent China Normal Univ, Coll Life Sci, Wuhan, Peoples R China.
[Qu, Y.] Wuhan Ctr Med Therapeut, Wuhan, Peoples R China.
[Xu, A.] Univ Hong Kong, Dept Pharmacol & Pharm, Hong Kong, Hong Kong, Peoples R China.
通讯机构:
[Huang, Q.] C
Cent China Normal Univ, Coll Life Sci, Wuhan, Peoples R China.
语种:
英文
关键词:
FABP2;Meta-analysis;Metabolic syndrome;Obesity;Type 2 diabetes mellitus
期刊:
Genetics and Molecular Research
ISSN:
1676-5680
年:
2015
卷:
14
期:
1
页码:
1155-1168
基金类别:
National Basic Research Program of China ("973" Program)National Basic Research Program of China [2011CB504004]; Self-Determined Research Funds of the Central China Normal University from the colleges' basic research and Operation of Ministry of Education [CCNU14Z01003]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Previous studies have reported associations between the functional FABP2 Ala54Thr (rs1799883) polymorphism and type 2 diabetes mellitus (T2DM), obesity, and metabolic syndrome in different populations with conflicting results. We investigated the association between the FABP2 Ala54Thr polymorphism and T2DM (235 cases, 431 controls), obesity (377 cases, 431 controls), and metabolic syndrome (315 cases, 323 controls) by logistic regression analysis in a Chinese study cohort recruited from Yichang, Hubei Province. We then comprehensively reviewed the association of the FABP2 Ala54Thr polymorphism...

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