In recent years,tandem cyclization has emerged as a versatile and economical strategy for the synthesis of highly functionalized polycyclic ring systems,which has attracted substantial interest from chemists.In particular,tandem double cyclization has found wide applications in total synthesis of natural products because of its advantages in unparalleled efficiencies,reducing the reaction steps and waste production.1 4,9-Dihydropyrrolo[2,1-b]quinazoline and its derivatives can be found in numerous natural products and biologically active molecu...