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Virus-host Association Prediction by using Kernelized Logistic Matrix Factorization on Heterogeneous Networks

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成果类型:
会议论文
作者:
Liu, Dan;Hu, Xiaohua;He, Tingting(何婷婷);Jiang, Xingpeng*蒋兴鹏
通讯作者:
Jiang, Xingpeng(蒋兴鹏
作者机构:
[Jiang, Xingpeng; He, Tingting; Hu, Xiaohua; Liu, Dan] Cent China Normal Univ, Sch Comp, Wuhan, Hubei, Peoples R China.
通讯机构:
[Jiang, Xingpeng] C
Cent China Normal Univ, Sch Comp, Wuhan, Hubei, Peoples R China.
语种:
英文
关键词:
Virus-host association;Heterogeneous network;Logistic matrix factorization;Neighborhood regularization;Oligonucleotide frequency;Gaussian interaction profile
期刊:
PROCEEDINGS 2018 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM)
ISSN:
2156-1125
年:
2018
页码:
108-113
会议名称:
IEEE International Conference on Bioinformatics and Biomedicine (BIBM) - Human Genomics
会议论文集名称:
IEEE International Conference on Bioinformatics and Biomedicine-BIBM
会议时间:
DEC 03-06, 2018
会议地点:
Madrid, SPAIN
会议主办单位:
[Liu, Dan;Hu, Xiaohua;He, Tingting;Jiang, Xingpeng] Cent China Normal Univ, Sch Comp, Wuhan, Hubei, Peoples R China.
会议赞助商:
Ulster Univ, Univ Granada, Univ Carlos III Madrid, TCCLS, IEEE, IEEE Comp Soc, Natl Sci Fdn, Syst Med, Mary Ann Liebert Inc publishers
主编:
Zheng, H Callejas, Z Griol, D Wang, H Hu, X Schmidt, H Baumbach, J Dickerson, J Zhang, L
出版地:
345 E 47TH ST, NEW YORK, NY 10017 USA
出版者:
IEEE
ISBN:
978-1-5386-5488-0
基金类别:
National Key Research and Development Program of China [2017YFC0909502]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61872157, 61532008]
机构署名:
本校为第一且通讯机构
院系归属:
计算机学院
摘要:
Virus-host association studies are significant for understanding the complex functions and dynamics of microbial communities of human health or diseases. Several virus-host association prediction methods have been developed based on the information of sequences, virus networks, host networks and virus-host networks separately. In this study, we develop a heterogeneous network approach based on neighborhood regularization logistic matrix factorization (LMFH-VH) which integrate the virus similarity network and the host similarity network using known virus-host associations. The virus similarity ...

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