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Cytochrome c1-like is required for mitochondrial morphogenesis and individualization during spermatogenesis in Drosophila melanogaster

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成果类型:
期刊论文
作者:
Chen, Meng-Yan;Duan, Xin;Wang, Qian;Ran, Mao-Jiu;Ai, Hui;...
通讯作者:
Zheng, Ya;Wang, YF
作者机构:
[Chen, Meng-Yan; Wang, Qian; Ran, Mao-Jiu; Wang, Yu-Feng; Ai, Hui; Zheng, Ya; Duan, Xin] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Wang, YF ; Zheng, Y] C
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Drosophila melanogaster;Cyt-c1L;Mitochondria;Individualization complexes;Spermatogenesis
期刊:
JOURNAL OF EXPERIMENTAL BIOLOGY
ISSN:
0022-0949
年:
2023
卷:
226
期:
3
页码:
jeb245277
基金类别:
National Natural Science Foundation of China [31872288, 31970471]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
The Drosophila testis is an excellent system for studying the process from germ stem cells to motile sperm, including the proliferation of male germ cells, meiosis of primary spermatocytes, mitochondrial morphogenesis, and spermatid individualization. We previously demonstrated that ocnus (ocn) plays an essential role in male germ cell development. Among those genes and proteins whose expression levels were changed as a result of ocn knockdown, cytochrome c1-like (cyt-c1L) was downregulated significantly. Here, we show that cyt-c1L is highly expressed in the testis of D. melanogaster. Knockdow...

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