期刊论文

Chen, MQ

英文

Science of The Total Environment

0048-9697

2024

922

171299

10.1016/j.scitotenv.2024.171299

CRediT authorship contribution statement Xiao Gao: Data curation, Investigation, Methodology, Validation, Writing – original draft. Ke Xu: Conceptualization, Investigation, Methodology. Wanting Du: Investigation, Methodology. Shuxin Wang: Investigation, Methodology. Mengling Jiang: Investigation. Yunyi Wang: Investigation, Software. Qi Han: Investigation, Software. Mingqing Chen: Conceptualization, acquisition, Methodology, Project administration, Supervision, Writing – review & editing.

本校为第一且通讯机构

After aging in the environment, some nanoplastics will carry different charges and functional groups, thereby altering their toxicological effects. To evaluate the potential impact of aging of nanoplastics on the mammalian reproductive system, we exposed C57BL/6 male mice to a dose of 5 mg/kg/d polystyrene nanoparticles (PS-NPs) with different functional groups (unmodified, carboxyl functionalized and amino functionalized) for 45 days for this study. The results suggest that PS-NPs with different functional groups triggered oxidative stress, a decreased in the testis index, disruption of the o...