期刊论文

Chen, Mingqing

英文

Toxicology

0300-483X

2023

486

153442

10.1016/j.tox.2023.153442

CRediT authorship contribution statement Shuwei Wang: Investigation, Validation, Methodology, Data curation, Writing – original draft. Qi Han: Investigation, Methodology, Conceptualization. Zhaolan Wei: Visualization, Software. Yunyi Wang: Investigation. Lingfu Deng: Resources. Mingqing Chen: Conceptualization, Methodology, Writing – review & editing, Project administration, acquisition, Supervision.

本校为第一机构

Previous studies suggest some link between formaldehyde exposure and harmful cardiovascular effects. But whether exposure to formaldehyde can cause blood pressure to rise, and if so, what the underlying mechanism is, remains unclear. In this study, C57BL/6 male mice were exposed to 0.1, 0.5, 2.5mg/m(3) of gaseous formaldehyde for 4hours daily over a three-week period. The systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP) and heart rate (HR) of the mice were measured by tail-cuff plethysmography, and any histopathological changes in the target organs of hy...