期刊论文

Lu, Liang-Qiu

英文

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

0002-7863

2017

139

41

14707-14713

10.1021/jacs.7b08310

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472057, 21572074, 21772052, 21772053]; Program of Introducing Talents of Discipline to Universities of China (111 Program) [B17019]; Foundation for the Author of National Excellent Doctoral Dissertation of PR ChinaFoundation for the Author of National Excellent Doctoral Dissertation of China [201422]; Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2015CFA033, 2017AH047]

本校为第一且通讯机构

Catalytic asymmetric cycloadditions of reactive ketene intermediates provide new opportunities for the production of chiral heterocyclic molecules. Though known for over 100 years, ketenes still remain underexplored in the field of transition-metal (TM)-catalyzed asymmetric cycloadditions because (1) ketenes, as highly electron-deficient species, are possibly unstable to low-valence TMs (i.e., decarbonylation or aggregation) and (2) the conventional thermal synthesis of ketenes from acyl chlorides and amines may be incompatible with TM catalysi...